This page has every Life Sciences Grade 12 Term 3 paper we have, from 2020 to 2026: 20 question papers and 20 memos in 85 PDFs. The papers were set by Eastern Cape, Gauteng, KwaZulu-Natal, Limpopo, Mpumalanga and Northern Cape. Files are in English, Afrikaans, isiXhosa and Sesotho. The newest year is first. Each paper shows the first page of questions, its marks and time, and what the questions cover. Below the papers there are 16 files of Term 3 study material.
Life Sciences Grade 12 Term 3 papers by year
Year Exams Papers PDFs
2026 September Trial 11 21 2025 September Trial 2 8 2023 September Trial 2 11 2022 September Trial 2 11 2021 September Trial 1 5 2020 September Trial 2 13
Topics that come up most in Life Sciences Grade 12 Term 3
Counted from the questions in the papers on this page: how many papers each topic appears in, and its average marks.
Topic Papers Average marks
Human endocrine system and homeostasis 2 50 Responding to the environment (humans) 2 50
Life Sciences Grade 12 Term 3 2025 question papers and memos
September Trial 2025 Paper 1
Life Sciences (Biology) Grade 12 September Trial 2025 Paper 1 question paper
150 marks · 2 h 30 min · 18 pages · 3 questions
What is in this paper (3 questions)
Q1
Human endocrine system and homeostasis 1.1 Various options are provided as possible answers to the following questions. 50 marks
Q2
Responding to the environment (humans) 2.1 Glue ear, also known as ‘otitis media with effusion,’ is a condition where fluid 50 marks
Q3
3.1 The diagram below is a female reproductive system showing development of 50 marks
Instructions to candidates Answer ALL the questions. Write ALL the answers in the ANSWER BOOK. Start the answer to EACH question at the top of a NEW page. Number the answers correctly according to the numbering system used in this question paper. Present your answers according to the instructions of each question. ALL drawings MUST be done in pencil and labelled in blue or black ink. Draw diagrams, tables or flow charts only when asked to do so. The diagrams in this question paper are NOT necessarily drawn to scale. Do NOT use graph paper. You must use a non-programmable calculator, protractor and a compass where necessary. All calculations to be rounded off to TWO decimal places. Write neatly and legibly.
September Trial 2025 Paper 2
150 marks · 2 h 30 min · 15 pages · 3 questions
What is in this paper (3 questions)
Q1
Genetics and inheritance 1.1 Various options are provided as possible answers to the following questions.
Q2
DNA and protein synthesis 2.1 The diagram below shows different processes involving a DNA molecule. 50 marks
Q3
3.1 Colour-blindness is a sex-linked genetic disease that is caused by a genetic 50 marks
Instructions to candidates Answer ALL the questions. Write ALL the answers in the ANSWER BOOK. Start the answer to EACH question at the top of a NEW page. Number the answers correctly according to the numbering system used in this question paper. Present your answers according to the instructions of each question. ALL drawings MUST be done in pencil and labelled in blue or black ink. Draw diagrams, tables or flow charts ONLY when asked to do so. The diagrams in this question paper are NOT necessarily drawn to scale. Do NOT use graph paper. You must use a non-programmable calculator, protractor and a compass, where necessary. All calculations to be rounded off to TWO decimal places. Write neatly and legibly.
Life Sciences Grade 12 Term 3 2023 question papers and memos
September Trial 2023 Paper 1
Life Sciences (Biology) Grade 12 September Trial 2023 Paper 1 question paper
150 marks · 2 h 30 min · 15 pages · 3 questions
What is in this paper (3 questions)
Q1
Human endocrine system and homeostasis 1.1 Various options are given as possible answers to the following questions.
Q2
Human reproduction 2.1 The diagram below represents different stages of development of the lining 50 marks
Q3
3.1 The diagram shows a reflex arc. 50 marks
Instructions to candidates Answer ALL the questions. Write ALL the answers in the ANSWER BOOK. Start the answer to EACH question at the top of a NEW page. Number the answers correctly according to the numbering system used in this question paper. Present your answers according to the instructions of each question. Do ALL drawings in pencil and label them in blue or black ink. Draw diagrams, tables or flow charts only when asked to do so. The diagrams in this question paper are NOT necessarily drawn to scale. Do NOT use graph paper. You may use a non-programmable calculator, protractor and a compass where necessary. Write neatly and legibly.
September Trial 2023 Paper 2
Life Sciences (Biology) Grade 12 September Trial 2023 Paper 2 question paper
150 marks · 2 h 30 min · 15 pages · 3 questions
What is in this paper (3 questions)
Q1
DNA and protein synthesis 1.1 Verskeie opsies word as moontlike antwoorde vir die volgende vrae gegee. Kies 50 marks
Q2
DNA and protein synthesis 2.1 Die onderstaande diagram toon ʼn gedeelte van die proses betrokke by die 50 marks
Q3
3.1 Lees die onderstaande uittreksel. 50 marks
Instructions to candidates Answer ALL the questions. Write ALL the answers in the ANSWER BOOK. Start the answer to EACH question at the top of a NEW page. Number the answers correctly according to the numbering system used in this question paper. Present your answers according to the instructions of each question. ALL drawings MUST be done in pencil and labelled in blue or black ink. Draw diagrams, tables or flow charts ONLY when asked to do so. The diagrams in this question paper are NOT necessarily drawn to scale. Do NOT use graph paper. You must use a non-programmable calculator, protractor and a compass, where necessary. All calculations to be rounded off to TWO decimal spaces. Write neatly and legibly.
Life Sciences Grade 12 Term 3 2022 question papers and memos
September Trial 2022 Paper 1
Life Sciences (Biology) Grade 12 September Trial 2022 Paper 1 question paper
150 marks · 2 h 30 min · 16 pages · 3 questions
What is in this paper (3 questions)
Q1
Responding to the environment (humans) 1.1 Various options are provided as possible answers to the following questions.
Q2
Reproduction in vertebrates 2.1 DIAGRAM I shows the structure of a normal female reproductive system and 50 marks
Q3
3.1 The diagram below shows part of the human ear. 50 marks
Instructions to candidates Answer ALL the questions. Write ALL the answers in your ANSWER BOOK. Start the answer to EACH question at the top of a NEW page. Number the answers correctly according to the numbering system used in this question paper. Present your answers according to the instructions of each question. Do ALL drawings in pencil and label them in blue or black ink. Draw diagrams, tables or flow charts only when asked to do so. The diagrams in this question paper are NOT necessarily drawn to scale. Do NOT use graph paper. You may use a non-programmable calculator, protractor and a compass where necessary. Write neatly and legibly.
September Trial 2022 Paper 2
Life Sciences (Biology) Grade 12 September Trial 2022 Paper 2 question paper
150 marks · 2 h 30 min · 16 pages · 3 questions
What is in this paper (3 questions)
Q1
Meiosis 1.1 Various options are provided as possible answers to the following questions.
Q2
Meiosis 2.1 A sequence of nitrogenous bases in a DNA molecule is shown below. 50 marks
Q3
3.1 Cloning is used to produce a variety of domestic animals. However, the cost to 50 marks
Instructions to candidates Answer ALL the questions. Write ALL the answers in the ANSWER BOOK. Start the answer to EACH question at the top of a NEW page. Number the answers correctly according to the numbering system used in this question paper. Present your answers according to the instructions of each question. ALL drawings MUST be done in pencil and labelled in blue or black ink. Draw diagrams, tables or flow charts ONLY when asked to do so. The diagrams in this question paper are NOT necessarily drawn to scale. Do NOT use graph paper. You must use a non-programmable calculator, protractor and a compass, where necessary. All calculations to be rounded off to TWO decimal spaces. Write neatly and legibly.
Life Sciences Grade 12 Term 3 2021 question papers and memos
September Trial 2021 Paper 1
Life Sciences (Biology) Grade 12 September Trial 2021 Paper 1 question paper
150 marks · 2 h 30 min · 16 pages · 3 questions
What is in this paper (3 questions)
Q1
Responding to the environment (humans) 1.1 Various options are provided as possible answers to the following questions.
Q2
Human reproduction 2.1 Read the extract below about reproduction in seahorses. 50 marks
Q3
3.1 A person had severe hearing loss which was caused by a damage to the 50 marks
Instructions to candidates Answer ALL the questions. Write ALL the answers in your ANSWER BOOK. Start the answer to EACH question at the top of a NEW page. Number the answers correctly according to the numbering system used in this question paper. Present your answers according to the instructions of each question. Do ALL drawings in pencil and label them in blue or black ink. Draw diagrams, tables or flow charts only when asked to do so. The diagrams in this question paper are NOT necessarily drawn to scale. Do NOT use graph paper. You may use a non-programmable calculator, protractor and a compass where necessary. Write neatly and legibly.
Life Sciences Grade 12 Term 3 2020 question papers and memos
September Trial 2020 Paper 1
Life Sciences (Biology) Grade 12 September Trial 2020 Paper 1 question paper
150 marks · 2 h 30 min · 16 pages · 4 questions
What is in this paper (4 questions)
Q1
Human endocrine system and homeostasis 1.1 Various options are provided as possible answers to the following questions.
Q2
Human endocrine system and homeostasis 2.1 The diagram below represents two stages of meiotic division. 40 marks
Q3
Human endocrine system and homeostasis 3.1 An experiment was conducted to determine the effect of the hormone thyroxin 40 marks
Q4
Mr Nkosi was trapped in a smoky room of a hotel which was on fire. His breathing rate 20 marks
Instructions to candidates Answer ALL the questions. Write ALL the answers in your ANSWER BOOK. Start the answer to EACH question at the top of a NEW page. Number the answers correctly according to the numbering system used in this question paper. Present your answers according to the instructions of each question. Do ALL drawings in pencil and label them in blue or black ink. Draw diagrams, tables or flow charts only when asked to do so. The diagrams in this question paper are NOT necessarily drawn to scale. Do NOT use graph paper. You may use a non-programmable calculator, protractor and a compass where necessary. Write neatly and legibly.
September Trial 2020 Paper 2
Life Sciences (Biology) Grade 12 September Trial 2020 Paper 2 question paper
150 marks · 2 h 30 min · 16 pages · 4 questions
What is in this paper (4 questions)
Q1
DNA and protein synthesis 1.1 Various options are provided as possible answers to the following questions.
Q2
DNA and protein synthesis 2.1 Study the diagram below. 40 marks
Q3
DNA and protein synthesis 3.1 Zebra fish come in many different colours. Emihle bought a blue male (BB) and 40 marks
Q4
Discuss the composition of the human karyotype. Also explain why meiosis is
Instructions to candidates Answer ALL the questions. Write ALL the answers in the ANSWER BOOK provided. Start the answer to EACH question at the top of a NEW page. Number the answers correctly according to the numbering system used in this question paper. Present your answers according to the instructions of each question. ALL drawings MUST be done in pencil and labelled in blue or black ink. Draw diagrams, tables or flow charts ONLY when asked to do so. The diagrams in this question paper are NOT necessarily drawn to scale. Do NOT use graph paper. You may use a non-programmable calculator, protractor and compass, where necessary. All calculations have to be rounded off to TWO decimal spaces. Write neatly and legibly.
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Life Sciences Grade 12 Term 3 study material
16 files for Term 3: notes, memo and addendum.
Life Sciences Grade 12 Term 3 2026
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Notes Term 3 English Source: WCED ePortal · CC BY-NC-ND
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Notes Term 3 Afrikaans Source: WCED ePortal · CC BY-NC-ND
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Life Sciences Grade 12 Term 3 2025
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Notes Term 3 English Source: WCED ePortal · CC BY-NC-ND
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Life Sciences Grade 12 Term 3 2024
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Memo Paper 1 Trial exam Term 3 Afrikaans
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Memo Paper 1 Trial exam Term 3 English
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Memo Paper 2 Trial exam Term 3 Afrikaans
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Memo Paper 2 Trial exam Term 3 English
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Memo Paper 1 Trial exam Term 3 Afrikaans
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Memo Paper 1 Trial exam Term 3 English
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Memo Paper 2 Trial exam Term 3 Afrikaans
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Memo Paper 2 Trial exam Term 3 English
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Life Sciences Grade 12 Term 3 2023
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Life Sciences Grade 12 Term 3 2021
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Memo Paper 2 Trial exam Term 3 Afrikaans
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Memo Paper 2 Trial exam Term 3 English
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Life Sciences Grade 12 Term 3 2014
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Questions about these papers
Which years of Life Sciences (Biology) Grade 12 Term 3 papers are on this page? Papers from 2026, 2025, 2023, 2022, 2021, 2020. The newest year is at the top.
How many marks is the Life Sciences (Biology) Grade 12 Term 3 paper 1? Paper 1 is usually out of 150 marks and you get 2 h 30 min to write it.
How many marks is the Life Sciences (Biology) Grade 12 Term 3 paper 2? Paper 2 is usually out of 150 marks and you get 2 h 30 min to write it.
Are the memos included? Yes. 20 of the 20 papers on this page have their marking memo next to the question paper.
Is there Life Sciences (Biology) Grade 12 Term 3 study material on this page? Yes. 16 files for Term 3: notes, memo and addendum.
Which topics come up most in Paper 1? Human endocrine system and homeostasis and responding to the environment (humans), based on 2 papers on this page.
